A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin- 2-ones and thiones

نویسندگان

  • Zhanxiong Fang
  • Yulin Lam
چکیده

A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2-ones and thiones was developed. The reaction involves a one-pot reaction between oxalacetic acid, thiourea/urea, and aldehyde under microwave irradiation and provides the products in good yields and much shorter reaction times. 2010 Elsevier Ltd. All rights reserved.

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تاریخ انتشار 2011